CHAPTER 20: Unit 2. Active Sites at the Enzymes

The enzyme is in general bigger in size than the substrates (the reactants). Inside the enzyme there are active sites.

These active sites are found in interior of the three-dimensional tertiary structure of an enzyme.

The active sites have very specific structures that fit closely to the substrates’ structures.

The specific amino group R (belongs to the enzyme interior structure) within the active site react with the functional groups found on the substrates through hydrogen bonds, salt bridges and hydrophobic interactions. The substrate is held by such interactions for the reaction to progress.

Reference: https://en.wikipedia.org/wiki/Active_site#/media/File:Lock_and_key.png

Reference: https://www.slideshare.net/DeepakKumarGupta2/enzyme-50519282

Enzyme Specificity Types:Enzyme specificity mean that every reaction will need one specific enzyme.Enzyme / Substrate Specificity

Reference: https://slideplayer.com/slide/6899475/

The video below illustrates the enzyme – substrate specificity: